Key Statistics for Non-Hodgkin Lymphoma

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Non-Hodgkin lymphoma (NHL) is one of the most common cancers in the United States, accounting for about 4% of all cancers.

The American Cancer Society’s estimates for non-Hodgkin lymphoma in 2025 are:

  • About 80,350 people (45,140 males and 35,210 females) will be diagnosed with NHL. This includes both adults and children.
  • About 19,390 people will die from this cancer (11,060 males and 8,330 females).

Overall, the chance that a man will develop NHL in his lifetime is about 1 in 44; for a woman, the risk is about 1 in 54. But each person’s risk can be affected by a number of risk factors.

NHL can occur at any age. In fact, it is one of the more common cancers among children, teens, and young adults. Still, the risk of developing NHL increases throughout life, and more than half of people are 65 or older when they are first diagnosed.

Incidence rates have declined by about 1% per year for NHL since 2015. And from 2013 to 2022, the death rate decreased by about 2% per year.

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The American Cancer Society medical and editorial content team

Our team is made up of doctors and oncology certified nurses with deep knowledge of cancer care as well as editors and translators with extensive experience in medical writing.

Last Revised: January 16, 2025

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